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What is Anismus? Anismus is a medical condition, a cause of constipation and painful defecation. it consist other medical names include paradoxical puborectalis contraction and pelvic floor dyssynergia. It refers a malfunction of the puborectalis muscle and external anal sphincter during an attempted bowel motion. Anismus is mostly occurs in young children and women and in people with certain rectal problems. Causes of anismus : Causes of anismus are similar to constipation and it is probably a specific voluntary sphincter muscle abnormality. There are numbers of factors can cause the anismus like: • Dehydration or inadequate fluid • Lack of physical activity • Irritable bowel syndrome • Problems with the rectum or colon • Anismus is the real cause of constipation • Lack of some minerals and vitamin • Anxiety is a cause of anismus slow down bowel and resulting constipation Symptoms of Anismus : Symptoms are often same as constipation. Some symptoms include: • Constipation or pain with

What are myeloproliferative disorders? Myeloproliferative disorders are a group of disease or a subset of bone marrow disorder. Normally in this condition the bone marrow makes too many white blood cell, red blood cell or platelets which develop in to mature blood cell over time. Myeloproliferative disorders is a serious condition, may pause certain health risk, It may affected at any age of people. Mostly men are affected more likely than women. The myeloid stem is developing in to three type of blood cell like: Red blood cell that carry oxygen White blood cell fight from disease and infection Platelets help to prevent bleeding by causing blood clots. There are four types of myeloproliferative disorder which include: Polycythemia vera : It is a kind of disorder involving the red blood cells or erythrocyteso, occurs when the bone marrow produces too many blood cells. They cause